| Abstract
| - For the identification and characterization of the argyrophil cells in the pancreatic islets of man, correlative studies on stainable cells between the light and electron microscopy were performed. Direct silver impregnation for electron microscopic specimens were also applied. The A-cells of the pancreatic islets showed argyrophilla when stained with the methods of Bodian and Grimellus, whilst the D-cells exhibited strongly argyrophil reaction by the method of Hellerström and Hellman. Weak argyrophilla was seen in some D-cells, when the method of Bodian and Grimelius were used. No argyrophil reaction was observed in the B-cells or acinal cells. Secretory granules of the A-and D-cells were submicroscopically found to be selectively stained by the different argyrophil reactions. In the A-cells, the peripheral mantle of the secretory granules showed a positive reaction by the Bodian's method. On the other hand, the whole secretory granules of the D-cells were covered with silver grains when the method of Hellerström and Hellman was applied.
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