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À propos de : Electron Microscopic Studies of Medullary Synaptic Inputs to Vasopressin-containing Neurons in the Hypothalamic Paraventricular Nucleus        

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  • Electron Microscopic Studies of Medullary Synaptic Inputs to Vasopressin-containing Neurons in the Hypothalamic Paraventricular Nucleus
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  • We have observed the ascending projections from the lower brain stem to the magnocellular vasopressin-Iike immunoreactive (VP-LI) neurosecretory neurons in the paraventricular nucleus (PVN) using electron microscopy. The tissues were prepared by a double labeling technique combining anterograde tracing after iontophoretic injection of wheat germ agglutinin-coupled horseradish peroxidase (WGA-HRP) in the Al group (lateral reticular nucleus in the medulla oblongata) with VP immunocytochemistry. Both the WGA-HRP-labeled and the unlabeled axon terminals made synaptic contacts with VP-LI cell bodies and processes in the PVN. This indicates a direct synaptic influence of medullary Al group on the secretory activity of the VP-containing neurons in the hypothalamic paraventricular nucleus.
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  • 39.6.501
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