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Some evidence that continuous subcutaneous insulin infusion for type I diabetes improves glycaemic control compared with multiple daily injections, but few trials have compared CSII with MDI using newer insulin analogues
Updated systematic review suggests that cranberry juice is not effective at preventing urinary tract infection
Vitamin E increases prostate cancer risk in middle-aged men relative to placebo: no significant association observed with selenium, either alone or in combination with vitamin E
Limited good-quality evidence available on earwax removal methods; softeners more effective than no treatment, but evidence for irrigation or mechanical removal is equivocal
Diabetes management can be safely transferred to practice nurses
Expansion of nursing role in general practice: studies suggest patients think that nurses can manage simple conditions but have some concerns about knowledge and competence in some areas
Intensive dietary advice significantly improves HbA(1c) in people with type 2 diabetes who remain hyperglycaemic despite optimised drug treatment
Orlistat reduces weight but its cost-effectiveness remains unclear
Low-dose aspirin is associated with an increased risk of haemorrhage; but not in people with diabetes who have a high baseline rate of bleeding
Telemonitoring or structured telephone support for people with chronic heart failure reduces CHF-related hospital admissions; telemonitoring also reduces all-cause mortality
Polyethylene glycol more effective than lactulose for relief of chronic constipation
People with hyperlipidaemia who followed a dietary portfolio of cholesterol-lowering foods achieved a greater reduction in LDL cholesterol over 6 months than those who received advice to follow a low-saturated fat diet
General health checks may not reduce morbidity or mortality but do increase the number of new diagnoses
Nurse case management with a therapeutic algorithm for people living with diabetes, hypertension and raised LDL cholesterol: after 1 year 22% of those receiving the intervention have all three parameters under control versus 10% of those receiving usual care
Quality improvement strategies for diabetes management decrease HbA1c, cholesterol and blood pressure, and increase screening for disease complications
People with diabetes and self-reported severe hypoglycaemia have increased mortality risk over 5 years
Compared to standard physician care for diabetes, nurse specialists provide similar care in terms of quality of life
Consultations between nurse prescribers and patients with diabetes in primary care: a qualitative study of patient views
Primary care interventions for obesity: behavioural support, whether delivered remotely or in person, facilitates greater weight loss over 2 years than self-directed weight loss
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