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Standard medical care does not offer sufficient relief of non-specific chest pain leading to additional diagnostic testing of no clinical benefit
Intensive glucose control increased mortality and did not prevent cardiovascular events in type 2 diabetes
Review: early feeding and delayed feeding after PEG placement do not differ for complications or death within 72 hours
Water based pillows reduced pain and improved sleep and disability in patients with cervical pain
Discharge planning and home follow up by advanced practice nurses reduced hospital readmissions of elderly patients
Review: specially designed products to prevent or heal pressure sores are more effective than standard mattresses
Intensive geriatric rehabilitation reduced hospital stay and time to independent living in hip fracture patients with mild to moderate dementia
Parent training improved maternal wellbeing and reduced attention deficit hyperactivity disorder symptoms in children
Continuous topical heat was as effective as ibuprofen for dysmenorrhoea
A home based, nurse delivered exercise programme reduced falls and serious injuries in people ≥80 years of age
Review: some herbal medicines and plant extracts reduced pain and disability and improved function in osteoarthritis
Review: group based parenting programmes improve short term mental health in infants and toddlers
Review: NSAIDs and adjuvant treatments such as hypnosis can help to reduce cancer related pain
Review: the Prentif cervical cap was as effective as the diaphragm in preventing pregnancy, and the FemCap was not
Topical anaesthetic applied at triage reduced treatment time in children presenting to the emergency department with minor lacerations
Review: chemotherapy plus supportive care improves survival and quality of life in advanced or metastatic gastrointestinal cancer more than supportive care alone
A telephone psychotherapy programme improved clinical outcomes in patients beginning antidepressant treatment
Review: antioxidant supplementation does not reduce gastrointestinal cancer
Review: non-invasive interventions improve symptoms and psychological functioning in patients with lung cancer
Clinician advice, an interactive computer program, and motivational counselling during routine medical visits increased reported smoking abstinence among teens
Review: some evidence suggests that cognitive behaviour therapy may reduce chest pain in the short term in patients with non-specific chest pain and normal coronary anatomy
Multivitamin and multimineral supplements did not reduce reported infection days or related use of healthcare services in elderly people
Inhaled insulin added to or replacing 2 oral agents reduced haemoglobin A1c concentrations in type 2 diabetes
Review: once daily LMWH is as effective as twice daily LMWH for initial treatment of venous thromboembolism
Review: secondary prevention programmes with and without exercise reduced all cause mortality and recurrent myocardial infarction
Review: laxatives in the form of fibre reduce symptoms in patients with symptomatic haemorrhoids
Mechanical ventilation with heated humidifiers or with heat and moisture exchangers with microbiological filters did not reduce ventilator associated pneumonia in adults
Immediate or delayed prescribing of antibiotics reduced duration of symptoms in acute infective conjunctivitis
Addition of peak flow monitoring to symptom monitoring did not improve healthcare visits, quality of life, or lung function in older adults with moderate-to-severe asthma
Review: adequately randomised trials showed that mammography screening did not significantly reduce breast cancer, cancer, or all cause mortality but increased breast surgeries
Review: advance provision of emergency contraception increases its use but does not reduce unplanned pregnancies
Targeted, immediate antibiotics following a positive dipstick test may be the optimal management strategy
Review: compulsory community treatment does not improve social functioning or service use in people with severe mental illness
Review: intensified patient care may improve adherence to lipid-lowering medication in primary or secondary prevention of CV disease
Review: routine NG decompression after abdominal surgery delays return of bowel function and increases pulmonary complications
Home-based cardiac rehab was as effective as hospital-based rehab in improving cardiac risk factors
Daily fish improved lipid profiles in patients with type II diabetes and moderate exercise prevented the deterioration in glycaemic control
Review: patient education and counselling increase preventive behaviours
Early discharge after surgery for breast cancer was safe and well received by patients
A single session of music therapy decreased anxiety and improved relaxation in adults who required mechanical ventilation
A 42 day tapering course of dexamethasone reduced duration of assisted ventilation in very low birthweight infants, but increased risk of cerebral palsy at age 1 year
A school based intervention to reduce television use decreased adiposity in children in grades 3 and 4
Review: nursing interventions increase smoking cessation rates in adults
Comprehensive, in-hospital geriatric assessment plus an interdisciplinary home intervention after discharge reduced length of subsequent readmissions and improved functioning
Pelvic floor re-education reduced incontinence 1 year after radical prostatectomy
Multilayer bandaging followed by compression hosiery was more effective than hosiery alone in reducing lymphoedema of the limb
Routine primary immunisation using a longer needle resulted in fewer local reactions in infants
Review: alarm interventions reduce nocturnal enuresis in children
Preoperative pillow placement under the injured extremity had better analgesic effects than skin traction for hip fracture
Intensive insulin treatment reduced mortality and morbidity in critically ill patients
A specialist nurse intervention reduced hospital readmissions in patients with chronic heart failure
Enteral nutrition reduced postoperative complications but increased minor adverse effects in gastrointestinal cancer
Review: pentoxifylline with standard compression treatment improves healing of venous leg ulcers
Pharmacological and non-pharmacological interventions improve food intake in cancer related anorexia and cachexia
Mifepristone was more effective than the Yuzpe regimen for emergency contraception
Review: probiotics are effective in preventing antibiotic associated diarrhoea
Review: organisational change and patient directed strategies may increase adult immunisation and cancer screening
Review: exercise reduces bone loss from the spine in postmenopausal women
Review: oral or parenteral opioids alleviate dyspnoea
Review: day hospital is as effective as inpatient care but has lower costs for patients with acute psychiatric disorders
Changing patients’ position in bed after non-emergency coronary angiography reduced back pain
Review: regular inhaled short acting β2 agonists improve lung function in stable chronic obstructive pulmonary disease
A time limited, nurse led intervention reduced hospital readmissions in patients with asthma and a history of frequent admissions
Review: silver alloy catheters are more effective than standard catheters for reducing bacteriuria in adults in hospital having short term catheterisation
Review: long acting β2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease
Review: probiotics reduced diarrhoea at 3 days in children and adults with proven or presumed infectious diarrhoea
Review: levonorgestrel and mifepristone are effective emergency methods for preventing pregnancy after unprotected intercourse
A multifaceted, home based, environmental intervention reduced asthma related morbidity in children with atopic asthma
Fluoxetine plus cognitive behavioural therapy was most effective for adolescents with major depressive disorder
Fluconazole reduced the rate of recurrence of vulvovaginal candidiasis
Review: mild induced hypothermia does not reduce mortality or severe disability in moderate to severe head injury
A home based, physical activity intervention increased physical activity, fitness, and vigour and reduced fatigue in sedentary women with early stage breast cancer
Review: dietary intervention plus exercise is no better than dietary intervention alone for inducing long term weight loss
Management of critically ill patients with a pulmonary artery catheter did not reduce all cause mortality
A telephone intervention reduced combined all cause mortality or admission for worsening heart failure in chronic heart failure
Adding topical pale sulfonated shale oil to compression therapy and moist wound care reduced venous leg ulcer size but had no effect on complete wound healing after 20 weeks
The LiftTrainerTM programme was not more effective than a video for reducing back injury in jobs with repetitive lifting
Review: timing or administration route of nutritional support does not affect death or disability in head injury
Review: providing patients with written information about medicines does not guarantee increased knowledge
Irrigation of simple lacerations with tap water or sterile saline in the emergency department did not differ for wound infections
Decontamination of the nasopharynx and oropharynx with chlorhexidine reduced nosocomial infections in cardiac surgery
Review: effectiveness of intensive case management for severe mental illness depends on baseline hospital use and organisation
A probiotic drink prevented diarrhoea and Clostridium difficile-associated diarrhoea in older patients taking antibiotics
Telehome monitoring reduced readmissions and improved quality of life in heart failure or angina
Review: home-made and commercial spacers did not differ for delivery of inhaled β2 agonists in children with asthma or wheezing
Review: evidence of the effectiveness of hydrocolloids for healing pressure ulcers is limited
Review: culturally appropriate health education improves glycaemic control in members of ethnic minority groups with diabetes
Nurse led secondary prevention clinics improved health and decreased hospital admissions in patients with coronary heart disease
Pressure bandages after coronary angiography reduced bleeding, but increased discomfort
Counselling after a myocardial infarction improved mood for patients and their partners and decreased patient functional limitations
A behavioural intervention improved cognitive function and depression in elderly people in residential homes
Skin to skin contact with their mothers reduced pain reactions in healthy newborn infants during a heel lance
Oestrogen plus progestin increased venous thromboembolic disease in postmenopausal women with coronary artery disease
Review: graduated compression stockings prevent deep venous thrombosis in patients who are in hospital
Adjunctive nurse telehealth care reduced depressive symptoms and improved functioning
A cognitive behavioural family intervention reduced psychiatric morbidity in caregivers of patients with Alzheimer's disease
Amethocaine gel reduced pain during venipuncture in newborn infants
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