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The combination of nefazodone and psychotherapy was more effective than either treatment alone in chronic depression
Valproate for acute mania reduced neuroleptic administration and improved symptoms on mania and global function scales
Hypericum extract was as effective as imipramine but had fewer adverse effects in mild to moderate depression
Sertraline maintenance treatment reduced relapse and dropouts in post-traumatic stress disorder
Collaborative care improves health outcomes in older people with depression and arthritis
Review: in people with bipolar disorder, short term antidepressants improve clinical response, although tricyclics risk inducing mania
Adding cognitive therapy to minimal psychiatric care prevents short term, but not long term, relapse in people with bipolar disorder
Individual dietary education reduces olanzapine associated weight gain
About 26% of people in the US have an anxiety, mood, impulse control, or substance disorder
Intermittent explosive disorder is common, has an early age of onset and is associated with the development of other mental disorders in the US population
IMPACT collaborative care programme reduces suicide ideation in depressed older adults
Review: Atypical antipsychotics are effective adjuncts for treatment resistant depression but increase discontinuation due to adverse effects
Impulse control loss rapidly reversed by aripiprazole in a patient with concomitant bipolar disease type I and posttraumatic frontal lobe lesions
A depression management programme reduced depression in frequent users of healthcare but did not reduce healthcare visits
Cognitive treatment reduced symptoms and improved functioning in bipolar disorder
Review: lithium is effective in preventing relapse in mixed diagnoses of mood disorder and in bipolar disorder
Olanzapine reduces mania more effectively than divalproex, but has more adverse effects
Manual assisted cognitive behaviour therapy is as effective as treatment as usual for deliberate self harm, but is more cost effective
Review: lithium reduces relapse rates in people with bipolar disorder
Cannabis use increases risk of developing symptoms of mania
Individual placement and support programme increases rates of obtaining employment in people with severe mental illness
Increase in out-based physician diagnoses of bipolar disorder in youth in the USA
Family focused therapy shortens recovery time from depression but not mania in adolescents with bipolar disorder
Antidepressants combined with self-management of pain improves outcomes in people with comorbid pain and depression
What works for delirious catatonic mania?
Teaching patients to recognise early symptoms of relapse reduced manic relapses and improved social functioning in bipolar disorder
Lithium is more effective than placebo for preventing all relapses in patients with bipolar but not unipolar disorder
Review: rapid cycling bipolar disorder associated with female gender and bipolar type II subgroup
Minimal contact psychotherapy reduces the risk of major depression in people with subthreshold depression
Rapid cycling is equivalently prevalent in bipolar I and bipolar II disorder, and is associated with female gender and greater severity of illness
Quetiapine more effective than placebo for depression in bipolar I and II disorder
Review: long term use of antidepressants for bipolar disorder reduces depressive episodes but increases risk of mania
Child bipolar I disorder is associated with manic episodes in adulthood
Most patients with a first episode of major depressive disorder experienced multiple levels of depressive symptoms over time
The benefits of exposure therapy alone may last longer than sertraline alone or sertraline plus exposure therapy in social phobia
Family focused psychoeducational therapy decreases relapse and rehospitalisation in people with a manic episode and bipolar disorder
Cognitive therapy is more effective than fluoxetine in people with generalised social phobia
Collaborative care depression management for older adults: level of comorbidity does not affect outcome
Adding repetitive transcranial magnetic stimulation to antidepressants does not improve response in people with depression
Antipsychotic-induced urinary dysfunction: anticholinergic effect or otherwise?
Family focused therapy is more effective than crisis management for preventing relapse after a bipolar episode
ICD-10 predicts risk of relapse and suicide in people diagnosed with a single depressive episode
PEARLS home based treatment significantly improves depression, dysthymia, and health related quality of life in older people
Individualised treatment improves depression in people with depression and diabetes
Long acting injectable naltrexone is effective and safe for treating alcohol dependence
Haloperidol, olanzapine and risperidone reduce treatment failure compared to aripiprazole, quetiapine and ziprasidone in acute schizophrenia
Severe mental illness increases the risk of death from coronary heart disease or stroke
Escitalopram modestly improves generalised anxiety disorder in older adults in treatment completers
Interpersonal therapy alone and supportive therapy plus antidepressant drugs were most effective for depression in HIV positive patients
Prodromal symptoms may be identified by people with bipolar or unipolar depression
Group psychoeducation reduces recurrence and hospital admission in people with bipolar disorder
Cognitive therapy is more cost effective than standard care alone for bipolar disorder
Risperidone maintenance treatment increases time to symptom recurrence in young people with disruptive behaviour disorders
Individual placement and support led to more competitive employment than did enhanced vocational rehabilitation for severe mental disorder
Lithium reduced aggression and was safe in aggressive children and adolescents with conduct disorder admitted to hospital
Fluoxetine may prevent relapse in post traumatic stress disorder
Fluoxetine improves minor depressive disorders
Paroxetine improves social anxiety disorder in children and adolescents
Topiramate improves psychopathological symptoms and quality of life in women with borderline personality disorder
Substance use and a history of psychosis are risk factors for serious adverse events in people with bipolar disorder
History of severe mental illness is more common in men convicted of a sexual offence than in men in the general population
Psychological function is mildly impaired for prolonged periods before and after first unipolar major depressive episode
Chronic, long episode mania exists in children
Review: Training patients to recognise and manage early warning signs delays recurrence of bipolar disorder
Major depressive disorder: afternoon and evening diurnal mood variation is common
Mortality in people with dementia taking antipsychotics higher than in those taking other psychiatric medications
Quetiapine-induced manic episode: a paradox for contemplation
Review: repetitive transcranial magnetic stimulation is of unknown effectiveness in people with depression
Lamotrigine and lithium are effective maintenance treatments in recently depressed people with bipolar I disorder
Stable monotherapy with clozapine or olanzapine increases the incidence of diabetes mellitus in people with schizophrenia
Risperidone effectively increases rates of symptomatic remission of acute mania in people with bipolar disorder
Review: an early sustained response can occur in the first and second weeks of antidepressant treatment for major depressive disorder
Review: antidepressant plus antipsychotic increases clinical response rates in psychotic depression
Intramuscular haloperidol plus promethazine is more effective and safer than haloperidol alone for rapid tranquillisation of agitated mentally ill patients
CBT improves worry severity in older adults with GAD in primary care
Review: twin studies show that genes and individual environmental influences contribute to the aetiology of major depression
The addition of olanzapine to valproate or lithium for acute manic or mixed bipolar episodes reduced manic symptoms
Review: cognitive therapy may be no more effective than other bona fide psychological therapies for depression
Flexible oral olanzapine dosing in acutely agitated people is immediately effective in reducing symptoms
Functional recovery is limited in people with bipolar disorder
Sertraline improves depression scores in the elderly in the short term, regardless of medical comorbidity status
Valproate reduces alcohol consumption in people with comorbid alcohol dependency and bipolar disorder
Adding a nurse-based intervention programme to usual care improves manic symptoms in people with bipolar disorder
Eye movement desensitisation and reprocessing reduces PTSD symptoms compared with fluoxetine at six months post-treatment
Quetiapine may reduce hospital admission rates in patients with mental health problems and alcohol addiction
Review: assertive community treatment is an effective alternative in severe mental disorders
Review: hippocampal volume is reduced in people with unipolar depression
Young people admitted with self-injury had more severe psychiatric disorders in 2000 than in 1990
Review: atypical antipsychotics are effective for treating bipolar mania
Bipolar I disorder is common in first-degree relatives of children with prepubertal and early adolescent bipolar I disorder
Toddler-parent psychotherapy increases secure attachment between toddlers and mothers who have experienced major depressive disorder
Major psychiatric disorders increase risk of mortality
Patients with early adolescent bipolar disorder had 37.1% recovery and 38.3% relapse rates
Risk of dementia in people with depressive and bipolar disorders increases with increasing number of prior affective episodes
Lifetime prevalence of psychotic disorders in Finland is 3.1%
Review: Intensive case management for severe mental illness reduces rehospitalisation when previous hospital use has been high
Successful treatment of acute mania and perineal abscess using dexmedetomidine sedation as adjunctive therapy
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