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Attributs	Valeurs
type	Concept
rdfs:label	CARCINOGENESIS Carcinogenesis
skos:inScheme	http://hub.abes.fr/referentiel/ouparticlecategories
is Subject of	The role of the C′ terminus of murine p53 in the p53/mdm-2 regulatory loop Reduction of hepatocarcinogenesis by ursodeoxycholic acid in rats Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin) Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate p53 codon 72 polymorphism associated with risk of human papillomavirus-associated squamous cell carcinoma of the oropharynx in never-smokers The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis Vanadate-induced activation of activator protein-1: role of reactive oxygen species Strain differences of rats in the susceptibility to aberrant crypt foci formation by 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine: no implication of Apc and Pla2g2a genetic polymorphisms in differential susceptibility New studies on trans-anethole oxide and trans-asarone oxide Immunohistochemical localization of inducible nitric oxide synthase and 3-nitrotyrosine in rat liver tumors induced by N-nitrosodiethylamine Effect of black and green tea polyphenols on c-jun phosphorylation and H2O2 production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction Potentiation of epidermal growth factor-induced DNA synthesis in rat hepatocytes by phenobarbitone: possible involvement of oxidative stress and kinase activation Differential effects of toxic metal compounds on the activities of Fpg and XPA, two zinc finger proteins involved in DNA repair Effects of human intestinal flora on mutagenicity of and DNA adduct formation from food and environmental mutagens Transgenic rats carrying human c-Ha-ras proto-oncogenes are highly susceptible to N-methyl-N-nitrosourea mammary carcinogenesis Oxidative damage in an esophageal adenocarcinoma model with rats Oxyradicals and DNA damage Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C → A:T mutations of the TP53 tumor suppressor gene Activation of caspase-3 activity and apoptosis in MDA-MB-468 cells by Nω-hydroxy-L-arginine, an inhibitor of arginase, is not solely dependent on reduction in intracellular polyamines Rat oesophageal cytochrome P450 (CYP) monooxygenase system: comparison to the liver and relevance in N-nitrosodiethylamine carcinogenesis Growth and characterization of N-methyl-N-nitrosourea-induced mammary tumors in intact and ovariectomized rats Presence of benzo[a]pyrene diol epoxide adducts in target DNA leads to an increase in UV-induced DNA single strand breaks and supF gene mutations Acquisition of apoptotic resistance in arsenic-induced malignant transformation: role of the JNK signal transduction pathway Effects of genetic background on prostate and taste bud carcinogenesis due to SV40 T antigen expression under probasin gene promoter control Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation Low amounts of the DNA repair XPA protein are sufficient to recover UV-resistance The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk Induction of tumors in the colon and liver of the immunodeficient (SCID) mouse by 2-amino-3-methylimidazo[4,5-f ]quinoline (IQ)—modulation by long-chain fatty acids Effects of arsenic on telomerase and telomeres in relation to cell proliferation and apoptosis in human keratinocytes and leukemia cells in vitro Expression of activins C and E induces apoptosis in human and rat hepatoma cells Ultraviolet A and B differently induce intracellular protein expression in human skin melanocytes—a speculation of separate pathways in initiation of melanoma Carcinogenicity of dimethylarsinic acid in p53 heterozygous knockout and wild-type C57BL/6J mice The role of human alkyladenine glycosylase in cellular resistance to the chloroethylnitrosoureas Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NF-κB Use of genetically manipulated Salmonella typhimurium strains to evaluate the role of sulfotransferases and acetyltransferases in nitrofen mutagenicity Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAαC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes Stereoselective metabolism and tissue retention in rats of the individual enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2 The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo Oncogene regulation of tumor suppressor genes in tumorigenesis Genistein stimulates growth of human breast cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF-β1 haploinsufficiency Chronic exposure to 12-O-tetradecanoylphorbol-13-acetate represses sod2 induction in vivo: the negative role of p50 Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells The aryl hydrocarbon receptor (AhR) inhibits vanadate-induced vascular endothelial growth factor (VEGF) production in TRAMP prostates Epstein-Barr virus nuclear antigen 2 disrupts mitotic checkpoint and causes chromosomal instability AMP kinase signaling determines whether c-Jun N-terminal kinase promotes survival or apoptosis during glucose deprivation CCDC62/ERAP75 functions as a coactivator to enhance estrogen receptor beta-mediated transactivation and target gene expression in prostate cancer cells DNA double-strand break repair activities in mammary epithelial cells--influence of endogenous p53 variants Activation of thromboxane A2 receptors induces orphan nuclear receptor Nurr1 expression and stimulates cell proliferation in human lung cancer cells Dual role for Id2 in chemical carcinogen-induced skin tumorigenesis Association between common mtDNA variants and all-cause or colorectal cancer mortality Reduction of protein kinase C delta attenuates tenascin-C stimulated glioma invasion in three-dimensional matrix Epigenetic inactivation of the miR-34a in hematological malignancies Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein Differential Activation of Hepatic NF-κB in Rats and Hamsters by the Peroxisome Proliferators Wy-14,643, Gemfibrozil, and Dibutyl Phthalate Micromolar Concentrations of Sodium Arsenite Induce Cyclooxygenase-2 Expression and Stimulate p42/44 Mitogen-Activated Protein Kinase Phosphorylation in Normal Human Epidermal Keratinocytes Tumor Profile of Novel p53 Heterozygous Tg.AC (v-Ha-ras) Bitransgenic Mice Treated with Benzo(a)pyrene and Fed Dietary N-acetyl-L-cysteine (NAC) Linked Expression of Ah Receptor, ARNT, CYP1A1, and CYP1B1 in Rat Mammary Epithelia, in Vitro, Is Each Substantially Elevated by Specific Extracellular Matrix Interactions that Precede Branching Morphogenesis Effect of sulphur mustard on the initiation and elongation of transcription 32P-Postlabeling of a DNA adduct derived from 4,4′-methylenedianiline, in the olfactory epithelium of rats exposed by inhalation to 4,4′-methylenediphenyl diisocyanate The relationship between N-nitrosodimethylamine metabolism and DNA methylation in isolated rat hepatocytes Effects of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on human small airway epithelial cells and the protective effects of myo-inositol Tumor promotion by hydrogen peroxide in rat liver epithelial cells Decreased expression of glutathione S-transferase M1 in HPV16-transfected human cervical keratinocytes in culture Histopathology and gene expression changes in rat liver during feeding of fumonisin B1, a carcinogenic mycotoxin produced by Fusarium moniliforme Expression of cytochrome P450 2A3 in rat esophagus: relevance to N-nitrosobenzylmethylamine Okadaic acid mediates p53 hyperphosphorylation and growth arrest in cells with wild-type p53 but increases aberrant mitoses in cells with non-functional p53 Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure Oxazepam is mutagenic in vivo in Big Blue® transgenic mice Thapsigargin has similar effect on p53 protein response to benzo[a]pyrene-DNA adducts as TPA in mouse skin Cigarette smoke induces direct DNA damage in the human B-lymphoid cell line Raji A deficiency in a 230 kDa DNA repair protein in Fanconi anemia complementation group A cells is corrected by the FANCA cDNA Exposure-route-dependent DNA adduct formation by polycyclic aromatic hydrocarbons The in vivo genetic activity profile of the monofunctional nitrogen mustard 2-chloroethylamine differs drastically from its bifunctional counterpart mechlorethamine Regulation of prostaglandin endoperoxide H synthase-2 induction by dioxin in rat hepatocytes: possible c-Src-mediated pathway Kinetics of DNA adduct formation and removal in mouse hepatocytes following in vivo exposure to 5,9-dimethyldibenzo[c,g]carbazole Radiation carcinogenesis Molecular alterations of p73 in human esophageal squamous cell carcinomas: loss of heterozygosity occurs frequently; loss of imprinting and elevation of p73 expression may be related to defective p53 Acrylonitrile-induced morphological transformation in Syrian hamster embryo cells Tamoxifen induces endometrial and vaginal cancer in rats in the absence of endometrial hyperplasia DNA damage in human breast milk cells and its induction by ‘early’ and ‘late’ milk extracts Modulation of base excision repair by low density lipoprotein, oxidized low density lipoprotein and antioxidants in mouse monocytes One-electron oxidation is not a major route of metabolic activation and DNA binding for the carcinogen 7H-dibenzo[c,g]carbazole in vitro and in mouse liver and lung N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Effects of benzyl isothiocyanate and phenethyl isothiocyanate on benzo[a]pyrene metabolism and DNA adduct formation in the A/J mouse γ-Glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines Cytochrome P4501A2 (CYP1A2) activity and lung cancer risk: a preliminary study among Chinese women in Singapore Lobe-specific increases in malondialdehyde DNA adduct formation in the livers of mice following infection with Helicobacter hepaticus Photocarcinogenesis in human adult skin grafts Influence of nitric oxide on the generation and repair of oxidative DNA damage in mammalian cells Immunohistochemical detection of a substituted 1,N2-ethenodeoxyguanosine adduct by ω-6 polyunsaturated fatty acid hydroperoxides in the liver of rats fed a choline-deficient, L-amino acid-defined diet

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