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Attributs	Valeurs
type	Concept
rdfs:label	RISK ASSESSMENT Risk Assessment Risk assessment
skos:inScheme	http://hub.abes.fr/referentiel/ouparticlecategories
is Subject of	Bacterial Lipopolysaccharide Exposure Alters Aflatoxin B1 Hepatotoxicity: Benchmark Dose Analysis for Markers of Liver Injury Biologically Motivated Computational Modeling of Chloroform Cytolethality and Regenerative Cellular Proliferation Cytochrome P450 1A1 and 1B1 in Human Blood Lymphocytes Are Not Suitable as Biomarkers of Exposure to Dioxin-like Compounds: Polymorphisms and Interindividual Variation in Expression and Inducibility Effect of PBPK Model Structure on Interpretation of In Vivo Human Aqueous Dermal Exposure Trials Use of a Pharmacokinetic Model to Assess Chlorpyrifos Exposure and Dose in Children, Based on Urinary Biomarker Measurements Statistical Analysis of Nonmonotonic Dose-Response Relationships: Research Design and Analysis of Nasal Cell Proliferation in Rats Exposed to Formaldehyde Identification of a Critical Dose Level for Risk Assessment: Developments in Benchmark Dose Analysis of Continuous Endpoints Toxicological Interactions among Arsenic, Cadmium, Chromium, and Lead in Human Keratinocytes Dose-Incidence Modeling: Consequences of Linking Quantal Measures of Response to Depletion of Critical Tissue Targets Biomarkers of Exposure to 1,3-Butadiene as a Basis for Cancer Risk Assessment Hormesis Outperforms Threshold Model in National Cancer Institute Antitumor Drug Screening Database Estimates of Cancer Potency of 2,3,4,7,8-Pentachlorodibenzofuran Using Both Nonlinear and Linear Approaches Parallelogram Approach Using Rat-Human In Vitro and Rat In Vivo Toxicogenomics Predicts Acetaminophen-induced Hepatotoxicity in Humans N-acetyltransferase 2 Genotype Modification of Active Cigarette Smoking on Breast Cancer Risk among Hispanic and Non-Hispanic White Women Analysis of the CYP1A1 mRNA Dose-Response in Human Keratinocytes Indicates that Relative Potencies of Dioxins, Furans, and PCBs Are Species and Congener Specific Biologically Motivated Computational Modeling of Formaldehyde Carcinogenicity in the F344 Rat Physiologically Based Pharmacokinetic Model for Developmental Exposures to TCDD in the Rat Estimation of Benchmark Dose for Pancreatic Damage in Cadmium-Exposed Smelters Estimates of Cancer Potency of 2,3,7,8-Tetrachlorodibenzo(p)dioxin Using Linear and Nonlinear Dose-Response Modeling and Toxicokinetics Proposed Occupational Exposure Limits for Select Ethylene Glycol Ethers Using PBPK Models and Monte Carlo Simulations Analysis of Rodent Growth Data in Toxicology Studies Application of Physiologically Based Pharmacokinetic Modeling in Setting Acute Exposure Guideline Levels for Methylene Chloride A Regression Spline Model for Developmental Toxicity Data Modeling and Assaying Dioxin-Like Biological Effects for both Dioxin-Like and Certain Non-Dioxin-Like Compounds Bioassays of Shortened Duration for Drugs: Statistical Implications Dose-Response Modeling of Continuous Endpoints Recommended Relative Potency Factors for 2,3,4,7,8-Pentachlorodibenzofuran: The Impact of Different Dose Metrics An Adaptable Internal Dose Model for Risk Assessment of Dietary and Soil Dioxin Exposures in Young Children Estimation of the Upper Limit of Human Butyrylcholinesterase Dose Required for Protection against Organophosphates Toxicity: a Mathematically Based Toxicokinetic Model U-shaped Dose Response in Vasomotor Tone: A Mixed Result of Heterogenic Response of Multiple Cells to Xenobiotics Risk Assessment of N-nitrosodimethylamine Formed Endogenously after Fish-with-Vegetable Meals Non-Cancer Risk Assessment for Nickel Compounds: Issues Associated with Dose-Response Modeling of Inhalation and Oral Exposures Family Approach for Estimating Reference Concentrations/Doses for Series of Related Organic Chemicals A PBPK Modeling-Based Approach to Account for Interactions in the Health Risk Assessment of Chemical Mixtures A Comparison of Ratio Distributions Based on the NOAEL and the Benchmark Approach for Subchronic-to-Chronic Extrapolation Investigation of the Low-Dose Response in the In Vivo Induction of Micronuclei and Adducts by Acrylamide Nasal Epithelium as a Sentinel for Airborne Environmental Pollution Measurement of Arsenic Bioavailability in Soil Using a Primate Model Thresholds of Carcinogenicity in the ED01 Study A Mixture of Dioxins, Furans, and Non-ortho PCBs Based upon Consensus Toxic Equivalency Factors Produces Dioxin-Like Reproductive Effects Human and Rat Primary Hepatocyte CYP1A1 and 1A2 Induction with 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran, and 2,3,4,7,8-Pentachlorodibenzofuran Effects of Di-isononyl Phthalate, Di-2-ethylhexyl Phthalate, and Clofibrate in Cynomolgus Monkeys Acute, Subacute, and Subchronic Oral Toxicity Studies of 1,1-Dichloroethane in Rats: Application to Risk Evaluation Existence of a Threshold for Induction of Aberrant Crypt Foci in the Rat Colon with Low Doses of 2-Amino-1-methyl-6-phenolimidazo[4,5-b]pyridine Comparison of TCDD and PCB CYP1A Induction Sensitivities in Fresh Hepatocytes from Human Donors, Sprague-Dawley Rats, and Rhesus Monkeys and HepG2 Cells The PPARα-Humanized Mouse: A Model to Investigate Species Differences in Liver Toxicity Mediated by PPARα Environmental Tobacco Smoke, Cardiovascular Disease, and the Nonlinear Dose-Response Hypothesis An Approach for the Quantitative Consideration of Genetic Polymorphism Data in Chemical Risk Assessment: Examples with Warfarin and Parathion The Hormetic Dose-Response Model Is More Common than the Threshold Model in Toxicology A Toxicokinetic Model of Malathion and Its Metabolites as a Tool to Assess Human Exposure and Risk through Measurements of Urinary Biomarkers Short-term Oral Toxicity of Pentyl Ether, 1,4-Diethoxybutane, and 1,6-Dimethoxyhexane in Male Rats A Novel Flexible Approach for Evaluating Fixed Ratio Mixtures of Full and Partial Agonists Risks for Heart Disease and Lung Cancer from Passive Smoking by Workers in the Catering Industry Relative Oral Bioavailability of Arsenic from Contaminated Soils Measured in the Cynomolgus Monkey Investigations of the Use of Bioavailability Data to Adjust Occupational Exposure Limits for Active Pharmaceutical Ingredients Induction of CYP1A1 in Primary Rat Hepatocytes by 3,3′,4,4′,5-Pentachlorobiphenyl: Evidence for a Switch Circuit Element 2 Current address: CIIT-Centers for Health Research, Six Davis Drive, PO Box 12137, Research Triangle Park, NC 27709. Ethyl Acrylate Risk Assessment with a Hybrid Computational Fluid Dynamics and Physiologically Based Nasal Dosimetry Model A Method to Integrate Benchmark Dose Estimates with Genomic Data to Assess the Functional Effects of Chemical Exposure Physiologically Based Pharmacokinetic Model of Methyl Tertiary Butyl Ether and Tertiary Butyl Alcohol Dosimetry in Male Rats Based on Binding to α2u-Globulin Prediction of Organophosphorus Acetylcholinesterase Inhibition Using Three-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) Methods Vinyl Acetate-Induced Intracellular Acidification: Implications for Risk Assessment Risk Assessment of High-Energy Chemicals by in Vitro Toxicity Screening and Quantitative Structure-Activity Relationships Single Cell Analysis of Switch-Like Induction of CYP1A1 in Liver Cell Lines 1 Present address: CIIT-Centers for Health Research, Six Davis Drive, PO Box 12137, Research Triangle Park, NC 27709. Evaluation of the Potential Impact of Age- and Gender-Specific Pharmacokinetic Differences on Tissue Dosimetry 2 Current address: Novartis Pharmaceuticals, East Hanover, NJ 07936. Human Respiratory Tract Cancer Risks of Inhaled Formaldehyde: Dose-Response Predictions Derived From Biologically-Motivated Computational Modeling of a Combined Rodent and Human Dataset A Statistical Evaluation of Toxicity Study Designs for the Estimation of the Benchmark Dose in Continuous Endpoints Development of a Physiologically Based Pharmacokinetic Model for Deltamethrin in the Adult Male Sprague-Dawley Rat A Method to Determine Precise Benchmark Doses for Carbamate Anticholinesterases The Frequency of U-Shaped Dose Responses in the Toxicological Literature Development of a Quantitative Model Incorporating Key Events in a Hepatotoxic Mode of Action to Predict Tumor Incidence The application of a risk assessment strategy to determine air pollution modeling and monitoring policy Nonmonotonic Dose-Response Relationships: Mechanistic Basis, Kinetic Modeling, and Implications for Risk Assessment Dose-Response Modeling and Benchmark Calculations from Spontaneous Behavior Data on Mice Neonatally Exposed to 2,2′,4,4′,5-Pentabromodiphenyl Ether Genomic Signatures and Dose-Dependent Transitions in Nasal Epithelial Responses to Inhaled Formaldehyde in the Rat Quantitative Risk Analysis for N-Methyl Pyrrolidone Using Physiologically Based Pharmacokinetic and Benchmark Dose Modeling Chemical-Specific Adjustment Factors for Intraspecies Variability of Acetone Toxicokinetics Using a Probabilistic Approach

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