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À propos de : Antitumor activity of imidazolium-bisimidazole-tetrachlororuthenate (III)        

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type
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Subject
subtitle
  • A representative of a new class of inorganic antitumor agents
Title
  • Antitumor activity of imidazolium-bisimidazole-tetrachlororuthenate (III)
has manifestation of work
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Author
Abstract
  • Summary. The antitumor activity of imidazolium-bisimidazole-tetrachlororuthenate (III) against the P388 leukemia and against the B16 melanoma was investigated. The test compound showed high activity against these tumor models. The tumor inhibiting effect was in the range or better than the effects of the compounds cyclophosphamide, cisplatin, or 5-fluorouracil, which were tested as positive controls. The effective substance is a new, water soluble, anionic, nitrogen-heterocyclic coordinated, ruthenium species, exhibiting antitumor activity.
article type
publisher identifier
  • BF00400758
Date Copyrighted
  • 1986
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