This HTML5 document contains 27 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

PrefixNamespace IRI
vivohttp://vivoweb.org/ontology/core#
dctermshttp://purl.org/dc/terms/
n11http://hub.abes.fr/referentiel/bmjarticlecategories/subject/
n7http://hub.abes.fr/bmj/periodical/ard/2008/volume_67/issue_6/B35044CA5E2C55BDE053120B220AEE5A/m/
n13http://hub.abes.fr/bmj/periodical/ard/
n9http://hub.abes.fr/bmj/periodical/ard/2008/volume_67/issue_6/B35044CA5E2C55BDE053120B220AEE5A/authorship/
n2http://hub.abes.fr/bmj/periodical/ard/2008/volume_67/issue_6/B35044CA5E2C55BDE053120B220AEE5A/
bibohttp://purl.org/ontology/bibo/
rdachttp://rdaregistry.info/Elements/c/
n12http://hub.abes.fr/bmj/periodical/ard/2008/volume_67/issue_6/
hubhttp://hub.abes.fr/namespace/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n15http://hub.abes.fr/bmj/periodical/articletype/
rdawhttp://rdaregistry.info/Elements/w/
n4http://hub.abes.fr/referentiel/hwpjournalcoll/subject/
xsdhhttp://www.w3.org/2001/XMLSchema#
Subject Item
n2:w
rdf:type
bibo:Article rdac:C10001
dcterms:isPartOf
n12:w
dcterms:subject
n4:clinicaldiagnostictests n4:radiology n4:degenerativejointdisease n11:extendedreports n4:musculoskeletalsyndromes n4:radiologydiagnostics n4:inflammation n4:immunologyincludingallergy n4:connectivetissuedisease n4:rheumatoidarthritis
dcterms:title
Magnetic resonance imaging findings in 84 patients with early rheumatoid arthritis: bone marrow oedema predicts erosive progression
rdaw:P10072
n7:print n7:web
vivo:relatedBy
n9:3 n9:5 n9:2 n9:1 n9:4
dcterms:abstract
Objectives:. To examine the spectrum and severity of magnetic resonance imaging (MRI) findings in patients with early rheumatoid arthritis (RA), and to investigate the predictive value of MRI findings for subsequent development of conventional radiographic (CR) damage and MRI erosions. Methods:. 84 consecutive patients with RA with disease duration <1 year were enrolled. Patients were treated according to standard clinical practice, and evaluated at baseline, 3, 6 and 12 months by core measures of disease activity, conventional radiographs of both hands and wrists and MRI of the dominant wrist. MR images were scored according to the OMERACT rheumatoid arthritis magnetic resonance imaging score (RAMRIS), and conventional radiographs according to the van der Heijde modified Sharp score. Results:. MRI findings reflecting inflammation (synovitis, bone marrow oedema and tenosynovitis) decreased during follow-up, while there was a small increase in MRI erosion score and CR damage. The proportion of patients with erosive progression at 1 year was 48% for conventional radiography and 66% for MRI. Baseline MRI bone marrow oedema (score >2 RAMRIS units) was identified as an independent predictor of both CR (odds ratio = 2.77 (95% confidence interval (CI) 1.06 to 7.21)) and MRI erosive progression (B = 0.21 (95% CI 0.08 to 0.34)). Conclusions:. MRI findings were common in early RA, and MRI bone marrow oedema was an independent predictor of radiographic damage. These results suggest that MRI scans of the dominant wrist may help clinicians to determine which patients need early and aggressive treatment to avoid subsequent joint damage.
hub:articleType
n15:researcharticle
hub:publisher-id
ar71977
dcterms:alternative
Extended report
hub:isPartOfThisJournal
n13:w
bibo:pmid
17981915