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Modulation in Kinetics of Lactone Ring Hydrolysis of Camptothecins uponInteraction with Topoisomerase I Cleavage Sites on DNA
Dimerization of a His117Gly Azurin Mutant by ExternalAddition of 1,ω-Di(imidazol-1-yl)alkanes
A Search for Single Substitutions That Eliminate Enzymatic Function in a BacterialRibonuclease
A Structural Role for Glutamine 214 in Human Thymidylate Synthase
Proteolytic Cleavage of Urokinase-Type Plasminogen Activator by Stromelysin-1(MMP-3)
Salt Effects on Hydrophobic Interaction and Charge Screening in the Folding of aNegatively Charged Peptide to a Coiled Coil (Leucine Zipper)
Transient Kinetic Analysis of Adenosine 5‘-Triphosphate Binding-InducedConformational Changes in the Allosteric Chaperonin GroEL
Construction of a Novel Redox Protein by Rational Design: Conversion of aDisulfide Bridge into a Mononuclear Iron−Sulfur Center
Calf Spleen Purine Nucleoside Phosphorylase Complexed with Substrates andSubstrate Analogues,
Effect of Iron-Sulfur Cluster Environment in Modulating the ThermodynamicProperties and Biological Function of Ferredoxin from Pyrococcus furiosus
Repressive Effect on Oligonucleosome Transcription of the Core Histone TailDomains
The EGF Receptor Transmembrane Domain: 2H NMR Study of PeptidePhosphorylation Effects in a Bilayer Environment
Ultrafast Carotenoid Band Shifts Probe Structure and Dynamics in PhotosyntheticAntenna Complexes
Physicochemical and Biochemical Properties of 2‘,5‘-Linked RNA and2‘,5‘-RNA:3‘,5‘-RNA “Hybrid” Duplexes,
Direct Measurement of Small Ligand-Induced Conformational Changes in theAspartate Chemoreceptor Using EPR
13C NMR Studies of Vitamin C Transport and Its Redox Cycling in HumanErythrocytes
A Hydroxyl Group at Residue 216 Is Essential for Catalysis by HumanThymidylate Synthase
Structure and Orientation of the Oxygen-Evolving Manganese Complex of GreenAlgae and Higher Plants Investigated by X-ray Absorption Linear DichroismSpectroscopy on Oriented Photosystem II Membrane Particles
Pre-Steady-State Analysis of ATP Hydrolysis by Saccharomyces cerevisiae DNATopoisomerase II. 1. A DNA-Dependent Burst in ATP Hydrolysis
Participation of the 3‘-CCA of tRNA in the Binding of Catalytic Mg2+ Ions byRibonuclease P
UTP Is a Cofactor for the DNA Strand Exchange Reaction Performed by the RecAProtein of Escherichia coli
Steady State and Time-Resolved Fluorescence Study of Residual Structures in anUnfolded Form of Yeast Phosphoglycerate Kinase
Sequence Determinants of the Intrinsic Bend in the Cyclic AMP Response Element
Self-Association and Backbone Dynamics of the Hck SH2 Domain in the Free andPhosphopeptide-Complexed Forms
Understanding the Electronic Properties of the CuA Site from the Soluble Domainof Cytochrome c Oxidase through Paramagnetic 1H NMR
Intramolecular Proton Transfer from Multiple Sites in Catalysis by Murine CarbonicAnhydrase V
Caldesmon−Actin−Tropomyosin Contains Two Types of Binding Sites for MyosinS1
Lipid-Binding Characteristics of the Polybasic Carboxy-Terminal Sequence ofK-ras4B
Studying Receptor−Ligand Interactions Using Encoded Amino Acid Scanning
Circular Dichroism and Electron Microscopy of a Core Y61F Mutant of the F1Gene 5 Single-Stranded DNA-Binding Protein and Theoretical Analysis of CDSpectra of Four Tyr → Phe Substitutions
Chimeric β-EF3-α Hemoglobin (Ψ): Energetics of Subunit Interaction and LigandBinding
Crystal Structure of ErmC‘, an rRNA Methyltransferase Which Mediates AntibioticResistance in Bacteria
Domain Swapping between Na,K- and H,K-ATPase Identifies Regions That SpecifyNa,K-ATPase Activity
Histone H1 Binding Does Not Inhibit Transcription of Nucleosomal Xenopus laevisSomatic 5S rRNA Templates
Characterization of the Copper Chaperone Cox17 of Saccharomyces cerevisiae
Kinetic Analysis by Fluorescence of the Interaction between Ras and the CatalyticDomain of the Guanine Nucleotide Exchange Factor Cdc25Mm
Molecular Cloning of the cDNA Encoding the Carboxy-Terminal Domain ofChimpanzee Apolipoprotein(a): An Asp57 → Asn Mutation in Kringle IV-10 IsAssociated with Poor Fibrin Binding
Prion Protein Selectively Binds Copper(II) Ions
Site-Directed Mutagenesis of Phe 97 to Glu in Amicyanin Alters the ElectronicCoupling for Interprotein Electron Transfer from Quinol MethylamineDehydrogenase
Redox Dependent Changes at the Heme Propionates in Cytochrome c Oxidase fromParacoccus denitrificans: Direct Evidence from FTIR Difference Spectroscopy inCombination with Heme Propionate 13C Labeling
Thermodynamic Consequences of an Abasic Lesion in Duplex DNA Are StronglyDependent on Base Sequence
Modulation of Phospholipase A2 Activity by Aminoglycosides and Daptomycin: A Fourier Transform Infrared Spectroscopic Study
Probe Transfer with and without Membrane Fusion in a Fluorescence Fusion Assay
Pre-Steady-State Analysis of ATP Hydrolysis by Saccharomyces cerevisiae DNATopoisomerase II. 2. Kinetic Mechanism for the Sequential Hydrolysis of TwoATP
Structural Replacement of Active Site Monovalent Cations by the ε-Amino Groupof Lysine in the ATPase Fragment of Bovine Hsc70,
Structure and Intramodular Dynamics of the Amino-Terminal LIM Domain fromQuail Cysteine- and Glycine-Rich Protein CRP2,
Ca2+ Coordination to Backbone Carbonyl Oxygen Atoms in Calmodulin and OtherEF-Hand Proteins: 15N Chemical Shifts as Probes for Monitoring Individual-SiteCa2+ Coordination
Kinetic Evidence for a Readily Exchangeable Nucleotide at the Terminal Subunit ofthe Barbed Ends of Actin Filaments
Transfer RNA−Pseudouridine Synthetase Pus1 of Saccharomyces cerevisiaeContains One Atom of Zinc Essential for Its Native Conformation and tRNARecognition
Zinc-Substituted Hemoglobins: α- and β-Chain Differences Monitored byHigh-Resolution Emission Spectroscopy
Biochemical Characterization of the HIV-1 Integrase 3‘-Processing Activity and ItsInhibition by Phosphorothioate Oligonucleotides
Mechanism-Based Inactivation of Human Cytochrome P450 1A2 by Furafylline: Detection of a 1:1 Adduct to Protein and Evidence for the Formation of a NovelImidazomethide Intermediate
Mutational Analysis of Novel Effector Domains in Rac1 Involved in the Activationof Nicotinamide Adenine Dinucleotide Phosphate (Reduced) Oxidase
The Conformation of NADH Bound to Inosine 5‘-Monophosphate DehydrogenaseDetermined by Transferred Nuclear Overhauser Effect Spectroscopy
Characterization of D10S and K71E Mutants of Human Cytosolic Hsp70
Involvement of Glutamic Acid 278 in the Redox Reaction of the Cytochrome cOxidase from Paracoccus denitrificans Investigated by FTIR Spectroscopy
Loop I Can Modulate ADP Affinity, ATPase Activity, and Motility of DifferentScallop Myosins. Transient Kinetic Analysis of S1 Isoforms
Thermodynamics of the Interaction of the Escherichia coli Regulatory Protein TyrRwith DNA Studied by Fluorescence Spectroscopy
Molybdenum Cofactor Properties and [Fe-S] Cluster Coordination in Escherichiacoli Nitrate Reductase A: Investigation by Site-Directed Mutagenesis of theConserved His-50 Residue in the NarG Subunit
In Vitro Selected RNA Molecules That Bind to Elongation Factor Tu
Prodan Fluorescence Reflects Differences in Nucleotide-Induced ConformationalStates in the Myosin Head and Allows Continuous Visualization of the ATPaseReactions
The Role of Gly-4 of Human Cystatin A (Stefin A) in the Binding of TargetProteinases. Characterization by Kinetic and Equilibrium Methods of theInteractions of Cystatin A Gly-4 Mutants with Papain, Cathepsin B, andCathepsin L
Kinetic Folding Pathway of a Three-Disulfide Mutant of Bovine PancreaticRibonuclease A Missing the [40−95] Disulfide Bond
Spectroscopic Evidence for Interaction between Transmembrane Helices 3 and 5 inRhodopsin
Reductive and Oxidative Half-Reactions of Morphinone Reductase fromPseudomonasputida M10: A Kinetic and Thermodynamic Analysis
Structures of Five Mutants of Toxic Shock Syndrome Toxin-1 with ReducedBiological Activity,
Conformational Stability of Factor VIIa: Biophysical Studies of Thermal andGuanidine Hydrochloride-Induced Denaturation
Copper-Binding Amyloid Precursor Protein Undergoes a Site-SpecificFragmentation in the Reduction of Hydrogen Peroxide
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