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À propos de : Antiproliferative Effects of the Readily Extractable FractionsPrepared from Various Citrus Juices on Several Cancer Cell Lines        

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  • Antiproliferative Effects of the Readily Extractable FractionsPrepared from Various Citrus Juices on Several Cancer Cell Lines
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  • To eliminate the masking effect by flavonoid glycosides, which comprise ∼70% of conventionallyprepared sample, the readily extractable fraction from Citrus juice, which was prepared by adsorbingon HP-20 resin and eluting with ethanol and acetone from the resin, was subjected to antiproliferativetests against several cancer cell lines. Screening of 34 Citrus juices indicated that King (Citrusnobilis) strongly inhibited proliferation of all cancer cell lines examined. Sweet lime and Kabuchiinhibited three of the four cancer cell lines. In contrast, these samples were substantially lesscytotoxic toward normal human cell lines. Keywords: Citrus; readily extractable fraction; A549; B16 melanoma 4A5; CCRF-HSB-2;TGBC11TKB; human foreskin keratinocytes; human umbilical vein endothelial cells
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