| Abstract
| - The isotopically labeled compounds [5,6-2H2]hexanal (d-I), [2,3-2H2]-(E)-2-nonenal (d-II), [3,4-2H2]-(E,E)-2,4-nonadienal (d-III), and [3,4-2H2]-(E,E)-2,4-decadienal (d-IV) were prepared in good yieldsusing new or improved synthesis procedures. Labeling position, chemical purity, and isotopicdistribution of the compounds were characterized by various MS and NMR techniques. Thesemolecules are used as internal standards in quantification experiments based on isotope dilutionassay. Synthesis of d-I, d-III, and d-IV has not yet been reported in the literature. Keywords: Synthesis; isotope labeling; deuteration; flavor compounds; lipid degradation products;[5,6-2H2]hexanal; [2,3-2H2]-(E)-2-nonenal; [3,4-2H2]-(E,E)-2,4-nonadienal; [3,4-2H2]-(E,E)-2,4-decadienal; NMR; GC/MS; isotope dilution assay
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