| Abstract
| - Streptomyces padanus strain PMS-702 is an antagonist of Rhizoctonia solani AG-4, the causal agentof damping-off of cabbage. Treatment of cabbage seeds with the culture filtrate of S. padanus strainPMS-702 was effective in reducing the incidence of damping-off of cabbage. The major activeingredient from the culture filtrate of S. padanus strain PMS-702 was purified by silica gel columnchromatography and identified as the polyene macrolide, fungichromin, by NMR and mass spectraldata. Bioassay studies showed that fungichromin had a strong antifungal activity against R. solaniAG-4, and its minimum inhibitory concentration (over 90% inhibition) was found to be 72 μg/mL. Thisis the first report of fungichromin from S. padanus as an active ingredient for the control of Rhizoctoniadamping-off of cabbage. Keywords: Fungichromin; Streptomyces padanus; Rhizoctonia solani; biocontrol; antifungal substance;polyene macrolide
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