| Abstract
| - Sulfur-containing compounds contributing to health promotion in Allium species are produced viaenzymic and thermochemical reactions. Sulfur-containing amino acids and volatile organosulfurcompounds were prepared for an antioxidative assay. The inhibitory activity of S-alk(en)yl-l-cysteinesand their sulfoxides, volatile alk(en)yl disulfides and trisulfides, and vinyldithiins in Allium speciesagainst lipid hydroperoxide (LOOH) formation in human low-density lipoprotein (LDL) was examined.It was elucidated that the alk(en)yl substituents (methyl, propyl, and allyl) and the number of sulfuratoms in the compounds were important for the antioxidative activity. 3,4-Dihydro-3-vinyl-1,2-dithiin,which is produced by a thermochemical reaction of allyl 2-propenethiosulfinate, exhibited the highestantioxidative activity of human LDL among sulfur-containing compounds. Keywords: Allium species; sulfur-containing compounds; antioxidative activity; life-style-relateddiseases; low-density lipoprotein
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