Abstract
| - Investigation on the anthelminthic bioactive compounds of the ethanol extract of Tadehagi triquetrumresulted in the isolation of three new prenylated isoflavones, triquetrumones A (1), B (2), and C (3),and one new prenylated biisoflavanone, (R)-triquetrumone D (4), along with 16 known compounds,cyclokievitone (5), yukovanol (6), aromadendrin (7), kaempferol (8), astragalin (9), 2-O-methyl-l-chiro-inositol (10), galactitol (11), p-hydroxycinnamic acid (12), ursolic acid (13), betulinic acid (14),β-sitosterol (15), daucosterol (16), stigmasterol (17), stigmasta-5,22-dien-3-O-β-d-glucopyranoside(18), saccharose (19), and docosanoic acid (20). The structures of 1−4 were elucidated on the basisof spectroscopic and spectrometric methods. Compounds 1−3 displayed mild anthelminthic bioactivity,and compound 3 showed a significant binding ability to the estrogen receptor. Keywords: Tadehagi triquetrum; Papilionaceae; coumaronochromone; triquetrumones A, B, C, D;anthelminthic
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