| Abstract
| - In this paper we describe an Internet Java-based technology that allows scientists to make their analyticalsoftware available worldwide. The implementation of this technology is exemplified by programs for thecalculation of the lipophilicity and water solubility of chemical compounds available at http://www.lnh.unil.ch/∼itetko/logp. Both these molecular properties are key parameters in quantitative structure−activity relationshipstudies and are used to provide invaluable information for the overall understanding of the uptake distribution,biotransformation, and elimination of a wide variety of chemicals. The compounds can be analyzed in batchor single-compound mode. The single-compound analysis offers the possibility to compare our results withseveral popular lipophilicity calculation methods, including CLOGP, KOWWIN, and XLOGP. The chemicalcompounds are analyzed according to SMILES line notation that can be prepared with the JME moleculareditor of Peter Ertl. Conversion to SMILES from 56 formats is also available using the molecular structureinformation interchange hub developed by Pat Walters and Matt Stahl.
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