| Abstract
| - Bile acid-derived novel amphiphilic topology was designed and synthesized in the form ofsteroidal dimers. These dimers were tested for antifungal and antiproliferative activity in vitro.N,N3-Diethylenetriaminebis[cholic acid amide] was found to be active against C. albicans, Y.lipolytica, and B. poitrassi at nanomolar concentration and did not show any effect on cellproliferation. N1,N-Ethylenediaminebis[deoxycholic acid amide] totally inhibited the growthof human oral cancer (HEp-2) and human breast cancer (MCF-7) cells.
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