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Attributs	Valeurs
type	work Issue
Is Part Of	http://hub.abes.fr/acs/periodical/jmcmar/2005/volume_48
has manifestation of work	http://hub.abes.fr/acs/periodical/jmcmar/2005/volume_48/issue_4/m/print http://hub.abes.fr/acs/periodical/jmcmar/2005/volume_48/issue_4/m/web
Date Copyrighted	2005
Rights	Copyright © 2005 American Chemical Society
issue	4
Rights Holder	American Chemical Society
is Is Part Of of	8-Substituted Analogues of 3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-isopropyl-adenine: Highly Potent and Selective PDE4 Inhibitors Discovery and Cocrystal Structure ofBenzodiazepinedione HDM2 AntagonistsThat Activate p53 in Cells Structure-based Drug Discovery Using GPCR Homology Modeling: SuccessfulVirtual Screening for Antagonists of the Alpha1A Adrenergic Receptor Synthesis and Evaluation of S-Acyl-2-thioethyl Esters of Modified Nucleoside5‘-Monophosphates as Inhibitors of Hepatitis C Virus RNA Replication Extravascular Transport of Drugs in Tumor Tissue: Effect of Lipophilicity onDiffusion of Tirapazamine Analogues in Multicellular Layer Cultures Synthesis and Biological Evaluation of Dimeric RGD Peptide−PaclitaxelConjugate as a Model for Integrin-Targeted Drug Delivery Synthesis and Cellular Studies of Nonaggregated Water-SolublePhthalocyanines Synthesis and Evaluation of Double-Prodrugs against HIV. Conjugation of D4Twith 6-Benzyl-1-(ethoxymethyl)-5-isopropyluracil (MKC-442, Emivirine)-TypeReverse Transcriptase Inhibitors via the SATE Prodrug Approach Antithrombin Activation by Nonsulfated, Non-Polysaccharide Organic Polymer Modulation of MRP-1-Mediated Multidrug Resistance by IndomethacinAnalogues Degradation, Insulin Secretion, and Antihyperglycemic Actions of TwoPalmitate-Derivitized N-Terminal Pyroglutamyl Analogues ofGlucose-Dependent Insulinotropic Polypeptide Novel Inhibitors of Human Histone Deacetylases: Design, Synthesis, EnzymeInhibition, and Cancer Cell Growth Inhibition of SAHA-BasedNon-hydroxamates Synthesis and Biological Evaluation of a New Series of 2,3,5-Substituted[1,2,4]-Thiadiazoles as Modulators of Adenosine A1 Receptors and TheirMolecular Mechanism of Action Three-Dimensional Structure−Activity Relationships of Nonsteroidal Ligandsin Complex with Androgen Receptor Ligand-Binding Domain Optimization and Validation of a Docking-Scoring Protocol; Application toVirtual Screening for COX-2 Inhibitors Novel 2-Alkylamino-1,4-benzoxazine Derivatives as Potent NeuroprotectiveAgents: Structure−Activity Relationship Studies CH···O and CH···N Hydrogen Bonds in Ligand Design: A NovelQuinazolin-4-ylthiazol-2-ylamine Protein Kinase Inhibitor Discovery and Structure−ActivityRelationship of Quinuclidine Benzamidesas Agonists of α7 Nicotinic AcetylcholineReceptors The Role of Intracellularly Released Formaldehyde and Butyric Acid in theAnticancer Activity of Acyloxyalkyl Esters Synthesis of (±)-2-O-[4‘-(N-9‘ ‘-Purinyl)butyl] myo-Inositol 1,4,5-Tris(phosphate),a Potent Full Agonist at the d-myo-Inositol 1,4,5-Tris(phosphate) Receptor Design, Synthesis, and Biological Evaluation of Novel Potent and Selectiveαvβ3/αvβ5 Integrin Dual Inhibitors with Improved Bioavailability. Selection ofthe Molecular Core Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles asOrally Active, Irreversible Inhibitors of Human Epidermal Growth FactorReceptor-2 Kinase Activity Synthesis and Cytotoxic Evaluation of Novel Spirohydantoin Derivatives of theDihydrothieno[2,3-b]naphtho-4,9-dione System Fully 2‘-Modified OligonucleotideDuplexes with Improved in VitroPotency and Stability Compared toUnmodified Small Interfering RNA Minor Structural Modifications Convertthe Dual TP/CRTH2 AntagonistRamatroban into a Highly Selective andPotent CRTH2 Antagonist CoMFA, Synthesis, and Pharmacological Evaluation of(E)-3-(2-Carboxy-2-arylvinyl)-4,6-dichloro-1H-indole-2-carboxylic Acids: 3-[2-(3-Aminophenyl)-2-carboxyvinyl]-4,6-dichloro-1H-indole-2-carboxylic Acid, aPotent Selective Glycine-Site NMDA Receptor Antagonist 3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)-6-methylpyrimidin-2,4-dione (NBI 42902) as a Potent and Orally ActiveAntagonist of the Human Gonadotropin-Releasing Hormone Receptor. Design,Synthesis, and in Vitro and in Vivo Characterization Amino Acid Ester Prodrugs of the Antiviral Agent2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole as Potential Substratesof hPEPT1 Transporter Synthesis, Nicotinic Acetylcholine Receptor Binding, and AntinociceptiveProperties of 3‘-Substituted Deschloroepibatidine Analogues. Novel NicotinicAntagonists New Potential Antihistaminic Compounds. Virtual Combinatorial Chemistry,Computational Screening, Real Synthesis, and Pharmacological Evaluation Greater Than the Sum of Its Parts: Combining Models for Useful ADMETPrediction Mechanism of Cytotoxicity of Copper(I) Complexes of1,2-Bis(diphenylphosphino)ethane A New Method for Estimating the Importance of Hydrophobic Groups in theBinding Site of a Protein Comparison of Automated Docking Programs as Virtual Screening Tools Synthesis and Biological Evaluation of Neutral and Zwitterionic 3-CarboranylThymidine Analogues for Boron Neutron Capture Therapy Novel Anticholinesterases Based on the Molecular Skeletons of Furobenzofuranand Methanobenzodioxepine Antiviral Activity of Glycyrrhizic Acid Derivatives against SARS−Coronavirus Synthetic Multivalent Molecules: Concepts andBiomedical Applications By Seok-Ki Choi. Wiley-Interscience, Hoboken, NJ. 2004. xxvi + 418 pp. 16 ×24 cm. ISBN 0471563471. $99.95. Multivariate Design, Synthesis, and Biological Evaluation of Peptide Inhibitorsof FimC/FimH Protein−Protein Interactions in Uropathogenic Escherichia coli Identification from a Positional Scanning Peptoid Library of in Vivo ActiveCompounds That Neutralize Bacterial Endotoxins Novel [2‘,5‘-Bis-O-(tert-butyldimethylsilyl)-β-d-ribofuranosyl]-3‘-spiro-5‘ ‘-(4‘ ‘-amino-1‘ ‘,2‘ ‘-oxathiole-2‘ ‘,2‘ ‘-dioxide) Derivatives with Anti-HIV-1and Anti-Human-Cytomegalovirus Activity Chiral DNA Gyrase Inhibitors. 3. Probing the Chiral Preference of the ActiveSite of DNA Gyrase. Synthesis of 10-Fluoro-6-methyl-6,7-dihydro-9-piperazinyl-2H-benzo[a]quinolizin-20-one-3-carboxylic Acid Analogues Introduction to Enzyme and Coenzyme Chemistry. Second Edition By T. D. H. Bugg. BlackwellPublishing, Oxford, U.K. x + 304 pp. 17.5 × 24 cm.ISBN 1-4051-1452-5. $75.00. Improving Specificity vs BacterialThymidylate Synthases throughN-Dansyl Modulation of Didansyltyrosine Indazole Estrogens: Highly Selective Ligands for the Estrogen Receptor β Synthesis, Antitumor Evaluation, and Apoptosis-Inducing Activity ofHydroxylated (E)-Stilbenes Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop NewInhibitors of Type I Fatty Acid Synthase

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