| Abstract
| - Controlling the annealing kinetics of metal-ion-implanted silicon resulted in the evolution of metallicnanoclusters in dielectric silica nanowires in a single heat treatment. This metallic nanocluster/dielectricnanowire composite serves as an excellent surface-enhanced Raman (SER) substrate, exhibiting a sensitivityof 1 × 107 toward Interleukin-10, a cancer biomarker, with high spatial resolution. The new SER configurationalso separates the plasmon phenomenon of the adsorbate molecules from the electronic resonances of thesubstrate. Implementation of such a generic configuration on silicon (Si) would facilitate a wide variety ofapplications, which include integrated microRaman on chip, a multimodal sensing platform for biodiagnostics,and a sensitizing medium for enriching the optical activity of erbium (Er).
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