| Abstract
| - Glass-supported films of lipids and polydiacetylene were applied for visual detection and colorimetric fingerprintingof bacteria. The sensor films comprise polydiacetylene domains serving as the chromatic reporter interspersed withinlipid monolayers that function as a biomimetic membrane platform. The detection schemes are based on either visibleblue−red transitions or fluorescence transformations of polydiacetylene, induced by amphiphilic molecules secretedby proliferating bacteria. An important feature of the new film platform is the feasibility of either naked-eye detectionof bacteria or color analysis using conventional scanners. Furthermore, we find that the degrees of bacterially inducedcolor transformations depend both on the bacterial strains examined and the lipid compositions of the films. Accordingly,bacterial fingerprinting can be achieved through pattern recognition obtained by recording the chromatic transformationsin an array of lipid/PDA films having different lipid components.
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