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À propos de : Optimal control of stochastic phase-field models related to tumor growth        

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  • Optimal control of stochastic phase-field models related to tumor growth
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  • We study a stochastic phase-field model for tumor growth dynamics coupling a stochastic Cahn-Hilliard equation for the tumor phase parameter with a stochastic reaction-diffusion equation governing the nutrient proportion. We prove strong well-posedness of the system in a general framework through monotonicity and stochastic compactness arguments. We introduce then suitable controls representing the concentration of cytotoxic drugs administered in medical treatment and we analyze a related optimal control problem. We derive existence of an optimal strategy and deduce first-order necessary optimality conditions by studying the corresponding linearized system and the backward adjoint system.
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  • cocv190130
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  • © EDP Sciences, SMAI 2020
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  • EDP Sciences, SMAI
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