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Attributs	Valeurs
type	Concept
rdfs:label	REPRODUCTIVE AND DEVELOPMENTAL TOXICOLOGY Reproductive and Developmental Toxicology
skos:inScheme	http://hub.abes.fr/referentiel/ouparticlecategories
is Subject of	Modulation of Glutathione and Glutamate-L-cysteine Ligase by Methylmercury during Mouse Development Effects of in Utero Exposure to the Organophosphate Insecticide Fenitrothion on Androgen-Dependent Reproductive Development in the Crl:CD(SD)BR Rat Methoxychlor Metabolites May Cause Ovarian Toxicity Through Estrogen-Regulated Pathways Methoxychlor Induces Atresia of Antral Follicles in ERα-Overexpressing Mice Gestational and Lactational Exposure to Ethinyl Estradiol, but not Bisphenol A, Decreases Androgen-Dependent Reproductive Organ Weights and Epididymal Sperm Abundance in the Male Long Evans Hooded Rat Early-Life Exposure to Dimethoate-Induced Reproductive Toxicity: Evaluation of Effects on Pituitary-Testicular Axis of Mice Embryotoxic and Teratogenic Effects of the Combination of Bisphenol A and Genistein on In Vitro Cultured Postimplantation Rat Embryos Evaluation of the Developmental Toxicity of Methacrylamide and N,N′-Methylenebisacrylamide in Swiss Mice Subchronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Modulates the Pathophysiology of Endometriosis in the Cynomolgus Monkey α-Chlorohydrin Inhibits Glyceraldehyde-3-Phosphate Dehydrogenase in Multiple Organs as Well as in Sperm Evaluation of the Aromatase Inhibitor Fadrozole in a Short-Term Reproduction Assay with the Fathead Minnow (Pimephales promelas) Gene Expression Profile Induced by 17α-Ethynyl Estradiol, Bisphenol A, and Genistein in the Developing Female Reproductive System of the Rat Microtubules of the Mouse Testis Exhibit Differential Sensitivity to the Microtubule Disruptors Carbendazim and Colchicine Effect of Methylmercury on Midbrain Cell Proliferation during Organogenesis: Potential Cross-Species Differences and Implications for Risk Assessment Lack of Expression of EGF and TGF-α in the Fetal Mouse Alters Formation of Prostatic Epithelial Buds and Influences the Response to TCDD ARNT2 Is Not Required for TCDD Developmental Toxicity in Zebrafish Effects of In Utero and Lactational TCDD Exposure on Bone Development in Differentially Sensitive Rat Lines Apoptosis Induced by atRA in MEPM Cells Is Mediated through Activation of Caspase and RAR Mono-(2-ethylhexyl) Phthalate Rapidly Increases Celsr2 Protein Phosphorylation in HeLa Cells via Protein Kinase C and Casein Kinase 1 Two-Generation Reproductive Toxicity Study of Dietary Bisphenol A in CD-1 (Swiss) Mice The Inhibition of Embryonic Histone Deacetylases as the Possible Mechanism Accounting for Axial Skeletal Malformations Induced by Sodium Salicylate Evaluation of Endocrine Disrupting Effects of Nitrate after In Utero Exposure in Rats and of Nitrate and Nitrite in the H295R and T-Screen Assay Chronic Toxicity and Reversibility of Antifertility Effect of Immunization against Gonadotropin-Releasing Hormone in Male Rats and Rabbits The Laminin Binding Protein p40 Is Involved in Inducing Limb Abnormality of Mouse Fetuses as the Effects of Methoxyacetic Acid Treatment Effects of Low Concentrations of Organochlorine Compounds in Women on Calcium Transfer in Human Placental Syncytiotrophoblast Effects of Thalidomide on Developmental, Peri- and Postnatal Function in Female New Zealand White Rabbits and Offspring Radiation Exposure Impairs Luteinizing Hormone Signal Transduction and Steroidogenesis in Cultured Human Leydig Cells Variable In Vivo Embryoprotective Role for Ataxia-Telangiectasia-Mutated against Constitutive and Phenytoin-Enhanced Oxidative Stress in Atm Knockout Mice Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Stage-Related Increase in the Proportion of Apoptotic Germ Cells and Altered Frequencies of Stages in the Spermatogenic Cycle Following Gestational, Lactational, and Direct Exposure of Male Rats to p-Nonylphenol Fetal Mouse Phthalate Exposure Shows that Gonocyte Multinucleation is Not Associated with Decreased Testicular Testosterone Time-Dependent and Compartment-Specific Effects of In Utero Exposure to Di(n-butyl) Phthalate on Gene/Protein Expression in the Fetal Rat Testis as Revealed by Transcription Profiling and Laser Capture Microdissection Relationship between Embryonic Histonic Hyperacetylation and Axial Skeletal Defects in Mouse Exposed to the Three HDAC Inhibitors Apicidin, MS-275, and Sodium Butyrate Glucocorticoids Alter Craniofacial Development and Increase Expression and Activity of Matrix Metalloproteinases in Developing Zebrafish (Danio rerio) Cross-talk between the Akt and NF-κB Signaling Pathways Inhibits MEHP-Induced Germ Cell Apoptosis Chromosomal Mosaicism in Mouse Two-Cell Embryos after Paternal Exposure to Acrylamide Ethylene Glycol Monomethyl Ether-Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family Adding Insult to Injury: Effects of Xenobiotic-Induced Preantral Ovotoxicity on Ovarian Development and Oocyte Fusibility Physiological Role of the Aryl Hydrocarbon Receptor in Mouse Ovary Development Analysis of the Combined Osteolathyritic Effects of β-Aminopropionitrile and Diethyldithiocarbamate on Xenopus Development Perinatal Exposure to the Phthalates DEHP, BBP, and DINP, but Not DEP, DMP, or DOTP, Alters Sexual Differentiation of the Male Rat The Effects of Atrazine on Female Wistar Rats: An Evaluation of the Protocol for Assessing Pubertal Development and Thyroid Function Developmental Toxicity Studies in Rats and Rabbits on 2,4-Dichlorophenoxyacetic Acid and Its Forms Effects of Prenatal Testosterone Propionate on the Sexual Development of Male and Female Rats: A Dose-Response Study Bromochloroacetic Acid Exerts Qualitative Effects on Rat Sperm: Implications for a Novel Biomarker Evaluation of the Developmental Toxicity of Formamide in New Zealand White Rabbits Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. II: Postnatal Evaluation Pubertal Development in Female Wistar Rats following Exposure to Propazine and Atrazine Biotransformation By-Products, Diamino-S-Chlorotriazine and Hydroxyatrazine Alterations in Gene Expression Induced in Day-9 Mouse Embryos Exposed to Hyperthermia (HS) or 4-Hydroperoxycyclophosphamide (4CP): Analysis Using cDNA Microarrays Evaluation of the Developmental and Reproductive Toxicity of Methoxychlor using an Anuran (Xenopus tropicalis) Chronic Exposure Model Testicular Toxicity of Candidate Fuel Additive 1,6-Dimethoxyhexane: Comparison with Several Similar Aliphatic Ethers Kinetics of Genistein and Its Conjugated Metabolites in Pregnant Sprague-Dawley Rats Following Single and Repeated Genistein Administration 7,12-Dimethylbenz[a]anthracene Interferes with the Development of Cultured Mouse Mandibular Molars Methoxychlor Inhibits Growth and Induces Atresia of Antral Follicles through an Oxidative Stress Pathway Role of AHR2 in the Expression of Novel Cytochrome P450 1 Family Genes, Cell Cycle Genes, and Morphological Defects in Developing Zebra Fish Exposed to 3,3′,4,4′,5-Pentachlorobiphenyl or 2,3,7,8-Tetrachlorodibenzo-p-dioxin The Aryl Hydrocarbon Receptor Affects Distinct Tissue Compartments during Ontogeny of the Immune System Human Primordial Germ Cell Formation Is Diminished by Exposure to Environmental Toxicants Acting through the AHR Signaling Pathway Modified Expression of Several Sperm Proteins after Chronic Exposure to the Antiandrogenic Compound Vinclozolin Effects of Acetaminophen on Preimplantation Embryo Glutathione Concentration and Development in Vivo and in Vitro Region-Specific Inhibition of Prostatic Epithelial Bud Formation in the Urogenital Sinus of C57BL/6 Mice Exposed in Utero to 2,3,7,8-Tetrachlorodibenzo-p-dioxin The α, β, γ, ∂-Unsaturated Aldehyde 2-trans-4-trans-Decadienal Disturbs DNA Replication and Mitotic Events in Early Sea Urchin Embryos Developmental Toxicity of the Dithiocarbamate Pesticide Sodium Metam in Zebrafish Methoxychlor Induces Proliferation of the Mouse Ovarian Surface Epithelium Induction of Cell-Cycle Arrest by all-trans Retinoic Acid in Mouse Embryonic Palatal Mesenchymal (MEPM) Cells Activator Protein-1 (AP-1) DNA Binding Activity Is Induced by Hydroxyurea in Organogenesis Stage Mouse Embryos Accumulation, Tissue Distribution, and Maternal Transfer of Dietary 2,3,7,8,-Tetrachlorodibenzo-p-Dioxin: Impacts on Reproductive Success of Zebrafish Characterizing the Ovotoxicity of Cyclophosphamide Metabolites on Cultured Mouse Ovaries Aryl Hydrocarbon Receptor Activation Impairs Extracellular Matrix Remodeling during Zebra Fish fin Regeneration Developmental Changes in Testicular Sensitivity to Estrogens throughout Fetal and Neonatal Life Retinoic Acid Receptor Gamma-Induced Misregulation of Chondrogenesis in the Murine Limb Bud In Vitro Nicotine Diminishes Testicular Gametogenesis, Steroidogenesis, and Steroidogenic Acute Regulatory Protein Expression in Adult Albino Rats: Possible Influence on Pituitary Gonadotropins and Alteration of Testicular Antioxidant Status Biological Effects and Dose-Response Assessment of Diesel Exhaust Particles on In Vitro Early Embryo Development in Mice Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. III. Candidate Gene Analysis Identifies a Role for Fas in the Attenuation of X-ray-Induced Apoptosis Toxicant-Induced Leakage of Germ Cell-Specific Proteins from Seminiferous Tubules in the Rat: Relationship to Blood-Testis Barrier Integrity and Prospects for Biomonitoring Assessment of the Developmental Toxicity, Metabolism, and Placental Transfer of Di-n-butyl Phthalate Administered to Pregnant Rats The Reproductive and Developmental Toxicity of the Antifungal Drug Nyotran® (Liposomal Nystatin) in Rats and Rabbits Prenatal Toxicity and Lack of Carcinogenicity of 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) following Transplacental Exposure Effect of Rodent Diets on the Sexual Development of the Rat Developmental Stage-Specific Effects of Perinatal 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure on Reproductive Organs of Male Rat Offspring A Study of the Potential for a Herbicide Formulation Containing 2,4-D and Picloram to Cause Male-Mediated Developmental Toxicity in Rats Effects of Dietary Restriction on Growth, Neurobehavior, and Reproduction in Developing Kunmin Mice Time- and Dose-Related Effects of Estradiol and Diethylstilbestrol on the Morphology and Function of the Fetal Rat Testis in Culture The Embryolethality of Lipopolysaccharide in CD-1 and Metallothionein I-II Null Mice: Lack of a Role for Induced Zinc Deficiency or Metallothionein Induction The Effect on Sperm Production in Adult Sprague-Dawley Rats Exposed by Gavage to Bisphenol A between Postnatal Days 91-97 Atrazine and the Hypothalamo-Pituitary-Gonadal Axis in Sexually Maturing Precocial Birds: Studies in Male Japanese Quail The Developmental Neurotoxicity of Fipronil: Notochord Degeneration and Locomotor Defects in Zebrafish Embryos and Larvae Marginal Zinc Deficiency Exacerbates Bone Lead Accumulation and High Dietary Zinc Attenuates Lead Accumulation at the Expense of Bone Density in Growing Rats The Role of the Aryl Hydrocarbon Receptor Pathway in Mediating Synergistic Developmental Toxicity of Polycyclic Aromatic Hydrocarbons to Zebrafish Sensitivity of Fetal Rat Testicular Steroidogenesis to Maternal Prochloraz Exposure and the Underlying Mechanism of Inhibition Changes in Reproductive Courtship Behaviors of Adult American Kestrels (Falco sparverius) Exposed to Environmentally Relevant Levels of the Polybrominated Diphenyl Ether Mixture, DE-71 Dose- and Route-Dependent Teratogenicity, Toxicity, and Pharmacokinetic Profiles of the Hedgehog Signaling Antagonist Cyclopamine in the Mouse Cadmium-Induced Differential Toxicogenomic Response in Resistant and Sensitive Mouse Strains Undergoing Neurulation Bisphenol A Exposure Induces Apoptosis and Upregulation of Fas/FasL and Caspase-3 Expression in the Testes of Mice Reproductive and Sphingolipid Metabolic Effects of Fumonisin B1 and its Alkaline Hydrolysis Product in LM/Bc Mice: Hydrolyzed Fumonisin B1 Did Not Cause Neural Tube Defects Induction of Testosterone Biotransformation Enzymes following Oral Administration of Methyl tert-Butyl Ether to Male Sprague-Dawley Rats BMS-189453, a Novel Retinoid Receptor Antagonist, Is a Potent Testicular Toxin

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