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IN VITRO TOXICOLOGY
In Vitro Toxicology
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Development of an Exonuclease Protection Mediated PCR Bioassay for Sensitive Detection of Ah Receptor Agonists
In Vitro Detection of Differential and Cell-Specific Hepatobiliary Toxicity Induced by Geldanamycin and 17-Allylaminogeldanamycin Using Dog Liver Slices
Interactions of Polybrominated Diphenyl Ethers with the Aryl Hydrocarbon Receptor Pathway
Copper-Induced Stimulation of Extracellular Signal-Regulated Kinase in Trout Hepatocytes: The Role of Reactive Oxygen Species, Ca2+, and Cell Energetics and the Impact of Extracellular Signal-Regulated Kinase Signaling on Apoptosis and Necrosis
Underlying Mechanisms of Pharmacology and Toxicity of a Novel PPAR Agonist Revealed Using Rodent and Canine Hepatocytes
Comparative Microarray Analysis of Basal Gene Expression in Mouse Hepa-1c1c7 Wild-Type and Mutant Cell Lines
Oxidative Stress Induces Internalization of the Bile Salt Export Pump, Bsep, and Bile Salt Secretory Failure in Isolated Rat Hepatocyte Couplets: A Role for Protein Kinase C and Prevention by Protein Kinase A
Mechanisms of Induction of Cell Cycle Arrest and Cell Death by Cryptolepine in Human Lung Adenocarcinoma A549 Cells
Azaspiracid-1 Alters the E-cadherin Pool in Epithelial Cells
In Vitro Toxicity of Kava Alkaloid, Pipermethystine, in HepG2 Cells Compared to Kavalactones
Characterization of Chemically Induced Hepatotoxicity in Collagen Sandwiches of Rat Hepatocytes
Preferential Induction of CYP1A1 and CYP1B1 in CCSP-Positive Cells
Establishment of an In Vitro High-Throughput Screening Assay for Detecting Phospholipidosis-Inducing Potential
Trichostatin A Enhances Gap Junctional Intercellular Communication in Primary Cultures of Adult Rat Hepatocytes
Comparison of In Vitro and In Vivo Screening Models for Androgenic and Estrogenic Activities
Sequential Exposure to Cytokines Reflecting Embryogenesis: The Key for in vitro Differentiation of Adult Bone Marrow Stem Cells into Functional Hepatocyte-like Cells
Phenolphthalein and Bisacodyl: Assessment of Genotoxic and Carcinogenic Responses in Heterozygous p53 (+/−) Mice and Syrian Hamster Embryo (SHE) Assay
Distinct Cytotoxic Mechanisms of Pristine versus Hydroxylated Fullerene
Differential Activation of Nuclear Receptors by Perfluorinated Fatty Acid Analogs and Natural Fatty Acids: A Comparison of Human, Mouse, and Rat Peroxisome Proliferator-Activated Receptor-α, -β, and -γ, Liver X Receptor-β, and Retinoid X Receptor-α
Draize Rabbit Eye Test Compatibility with Eye Irritation Thresholds in Humans: A Quantitative Structure-Activity Relationship Analysis
Characterization of the Species-Specificity of Peroxisome Proliferators in Rat and Human Hepatocytes 1 Present address: GenPharmTox Biotech AG, 82152 Martinsried, Germany.
A Physiologically Based Pharmacokinetic Model of Organophosphate Dermal Absorption
Inducible Nitric Oxide Synthase and Apoptosis in Murine Proximal Tubule Epithelial Cells
The Histone Deacetylase Inhibitor Trichostatin A Has Genotoxic Effects in Human Lymphoblasts In Vitro
Involvement of Gelsolin in Cadmium-Induced Disruption of the Mesangial Cell Cytoskeleton
Surface Reactivity, Cytotoxic, and Morphological Transforming Effects of Diatomaceous Earth Products in Syrian Hamster Embryo Cells
Correlating Nanoscale Titania Structure with Toxicity: A Cytotoxicity and Inflammatory Response Study with Human Dermal Fibroblasts and Human Lung Epithelial Cells
Effect of Smoking Conditions and Methods of Collection on the Mutagenicity and Cytotoxicity of Cigarette Mainstream Smoke
Corneal Organ Culture Model for Assessing Epithelial Responses to Surfactants
Potentiation of Apoptosis by Heat Stress Plus Pesticide Exposure in Stress Resistant Human B-Lymphoma Cells and Its Attenuation through Interaction with Follicular Dendritic Cells: Role for c-Jun N-terminal Kinase Signaling
Each Lipase Has a Unique Sensitivity Profile for Organophosphorus Inhibitors
Molecular Characterization and Inhibition of Amanitin Uptake into Human Hepatocytes
Calpain-Induced Endoplasmic Reticulum Stress and Cell Death following Cytotoxic Damage to Renal Cells
Nrf2 Activation Involves an Oxidative-Stress Independent Pathway in Tetrafluoroethylcysteine-Induced Cytotoxicity
Embryonic Stem Cells in Predictive Cardiotoxicity: Laser Capture Microscopy Enables Assay Development
Penetration of Intact Skin by Quantum Dots with Diverse Physicochemical Properties
In Vitro Profiling of the Endocrine-Disrupting Potency of Brominated Flame Retardants
Validation and Development of a Predictive Paradigm for Hemotoxicology Using a Multifunctional Bioluminescence Colony-Forming Proliferation Assay
Identification of the Tryptophan Photoproduct 6-Formylindolo[3,2-b]carbazole, in Cell Culture Medium, as a Factor That Controls the Background Aryl Hydrocarbon Receptor Activity
Enhancement of Transformed Foci and Induction of Prostaglandins in Balb/c 3T3 Cells by Palytoxin: In Vitro Model Reproduces Carcinogenic Responses in Animal Models Regarding the Inhibitory Effect of Indomethacin and Reversal of Indomethacin's Effect by Exogenous Prostaglandins
ERK Activation in Arsenite-Treated G1-Enriched CL3 Cells Contributes to Survival, DNA Repair Inhibition, and Micronucleus Formation
Inhibition of Hepatobiliary Transport as a Predictive Method for Clinical Hepatotoxicity of Nefazodone
Identification of New Human Pregnane X Receptor Ligands among Pesticides Using a Stable Reporter Cell System
The Utility of the Guppy (Poecilia reticulata) and Medaka (Oryzias latipes) in Evaluation of Chemicals for Carcinogenicity
Interaction of Arsine with Hemoglobin in Arsine-Induced Hemolysis
Phenobarbital and Phenytoin Increased Acetaminophen Hepatotoxicity Due to Inhibition of UDP-Glucuronosyltransferases in Cultured Human Hepatocytes
Inhibition and Induction of Aromatase (CYP19) Activity by Brominated Flame Retardants in H295R Human Adrenocortical Carcinoma Cells
Activation of Mouse and Human Peroxisome Proliferator-Activated Receptors (α, β/δ, γ) by Perfluorooctanoic Acid and Perfluorooctane Sulfonate
Promyelocytic HL60 Cells Express NADPH Oxidase and Are Excellent Targets in a Rapid Spectrophotometric Microplate Assay for Extracellular Superoxide
2,3,5-tris(Glutathion-S-yl)hydroquinone (TGHQ)-Mediated Apoptosis of Human Promyelocytic Leukemia Cells Is Preceded by Mitochondrial Cytochrome c Release in the Absence of a Decrease in the Mitochondrial Membrane Potential
Resveratrol Protects Against 4-Hydroxynonenal-Induced Apoptosis by Blocking JNK and c-JUN/AP-1 Signaling
Investigation of Drug-Induced Mitochondrial Toxicity Using Fluorescence-Based Oxygen-Sensitive Probes
The Interaction of Manganese Nanoparticles with PC-12 Cells Induces Dopamine Depletion
A Study of the Relationship between Cornea Permeability and Eye Irritation Using Membrane-Interaction QSAR Analysis
Tracheobronchial Particle Dose Considerations for In Vitro Toxicology Studies
The Effects of Anticholinergic Insecticides on Human Mesenchymal Stem Cells
Determination of Phospholipidosis Potential Based on Gene Expression Analysis in HepG2 Cells
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